期刊
BIOTECHNOLOGY AND BIOENGINEERING
卷 93, 期 6, 页码 1138-1144出版社
WILEY-BLACKWELL
DOI: 10.1002/bit.20829
关键词
Baeyer-Villiger oxidation; cyclohexanone monooxygenase; in situ SFPR; oxygenation; oxygen transfer; whole cell biotransformation
Efficient whole cell biotransformations, in particular microbial whole cell Baeyer-Villiger oxidation with molecular oxygen, demand comprehension and optimization of the process details involved. Optimal provision of oxygen and control of bioprocess parameters are pivotal for their success. The interrelation of cell density and oxygen supply in an in situ substrate feeding and product removal (SFPR) whole cell Baeyer-Villiger oxidation process was investigated in detail. Both parameters were optimized with respect to practical considerations. The outcome of this study supports a schematic process model, allows estimation of optimum process conditions and exploration of its limits. (c) 2006 Wiley Periodicals, Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据