期刊
NEUROREPORT
卷 17, 期 6, 页码 671-674出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00001756-200604240-00023
关键词
finger sequence; interhemispheric inhibition; M1; primary motor cortex; motor recovery; tDCS; transcranial direct current stimulation
资金
- NINDS NIH HHS [NS053326, NS045049, F32 NS053326-01] Funding Source: Medline
Transcranial direct current stimulation over the left motor area influenced both contralateral and ipsilateral finger sequence movements in seven healthy adults. Effects for the two hands were reversed: anodal stimulation improved right-hand performance significantly more than cathodal stimulation, whereas cathodal stimulation improved left-hand performance significantly more than anodal stimulation. The results show that stimulating a motor region directly, or indirectly by modulating activity in the homologous region on the opposite hemisphere, can affect motor skill acquisition, presumably by facilitating effective synaptic connectivity. This outcome provides evidence for the role of interhemispheric inhibition in corticomotor functioning, and also has implications for treatment methods aimed at facilitating motor recovery after stroke.
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