期刊
TETRAHEDRON LETTERS
卷 47, 期 18, 页码 3145-3148出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2006.02.140
关键词
amine thiourea; asymmetric organocatalysis; enones; Michael addition reaction; thioacetic acid
An enantioselective, organocatalytic Michael addition reaction of thioacetic acid with enones has been developed. The process, catalyzed by a chiral bifunctional amine thiourea, furnishes products in excellent yields with tip to 63% cc. (c) 2006 Elsevier Ltd. All rights reserved.
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