期刊
JOURNAL OF FLUORINE CHEMISTRY
卷 127, 期 4-5, 页码 539-544出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2006.03.011
关键词
trifluoromethylation; Ti ate enolate; alpha-CF3 ketone; radical addition
The radical trifluoromethylation of ketone Ti ate enolates gave alpha-CF3 ketones in good yields. The use of excess amount of LDA and Ti((OPr)-Pr-i)(4) in the preparation of Ti ate enolates is the key to the efficient radical trifluoromethylation. Theoretical studies on the spin density of the Ti(IV) ate ketyl radical intermediate suggest the involvement of transformation from Ti(IV) ate ketyl radical intermediates to Ti(III) species in a radical termination step. (C) 2006 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据