期刊
MEMORIAS DO INSTITUTO OSWALDO CRUZ
卷 101, 期 3, 页码 307-313出版社
FUNDACO OSWALDO CRUZ
DOI: 10.1590/S0074-02762006000300015
关键词
dengue virus type 3; complete genome; Brazil
We have determined the complete nucleotide and the deduced amino acid sequences of Brazilian dengue virus type 3 (DENV-3) from a dengue case with fatal outcome, which occurred during an epidemic in the state of Rio de Janeiro, Brazil, in 2002. This constitutes the first complete genetic characterization of a Brazilian DENV-3 strain since its introduction into the country in 2001. DENV-3 was responsible for the most severe dengue epidemic in the state, based on the highest number of reported cases and on the severity of clinical manifestations and deaths reported.
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