期刊
AIDS AND BEHAVIOR
卷 10, 期 3, 页码 227-245出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10461-006-9078-6
关键词
HIV/AIDS; antiretroviral; medication adherence; self-report; viral load
资金
- NIAID NIH HHS [P30 AI 27757, P30 AI027757] Funding Source: Medline
- NIMH NIH HHS [F31 MH071179, R01 MH058986, F31 MH71179, 2 R01 MH58986] Funding Source: Medline
A review of 77 studies employing self-report measures of antiretroviral adherence published 1/1996 through 8/2004 revealed great variety in adherence assessment item content, format, and response options. Recall periods ranged from 2 to 365 days (mode = 7 days). The most common cutoff for optimal adherence was 100% (21/48 studies, or 44%). In 27 of 34 recall periods (79%), self-reported adherence was associated with adherence as assessed with other indirect measures. Data from 57 of 67 recall periods (84%) indicated self-reported adherence was significantly associated with HIV-1 RNA viral load; in 16 of 26 (62%), it was associated with CD4 count. Clearly, the field would benefit from item standardization and a priori definitions and operationalizations of adherence. We conclude that even brief self-report measures of antiretroviral adherence can be robust, and recommend items and strategies for HIV research and clinical management.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据