The impact of genomics on the analysis of host resistance to infectious disease

The advent of new technologies and resources, including the complete sequence of mammalian genomes, has had a dramatic impact on the genetic analysis of susceptibility to infections in humans and in animal models of infection. Genes responsible for simple or complex control of susceptibility to infection with different pathogens have been recently identified and characterized, and are reviewed herein. (c) 2006 Elsevier SAS. All rights reserved.