期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 6, 期 5, 页码 499-503出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955706776876131
关键词
imiquimod; imidazoquinolone; immune response modifier; toll-like receptor; skin infection; skin cancer
Imiquimod is a synthetic imidazoquinoline heterocyclic amine of 240.3 Da (C14H16N4). Imiquimod is a cytokine inducer and a modifier of the innate immune response, as well as acquired antiviral and antitumor immune responses. Imiquimod 5% cream has proven to be an effective treatment for external genital warts, superficial basal cell carcinoma, and actinic keratosis.
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