期刊
HUMAN MOLECULAR GENETICS
卷 15, 期 10, 页码 1563-1568出版社
OXFORD UNIV PRESS
DOI: 10.1093/hmg/ddi481
关键词
-
资金
- NICHD NIH HHS [HD034980-09] Funding Source: Medline
- NIMH NIH HHS [P30MH60575-05, K23MH001760, K01MH65580-03] Funding Source: Medline
Human intelligence is a trait that is known to be significantly influenced by genetic factors, and recent linkage data provide positional evidence to suggest that a region on chromosome 6p, previously associated with schizophrenia, may be linked to variation in intelligence. The gene for dysbindin-1 (DTNBP1) is located at 6p and has also been implicated in schizophrenia, a neuropsychiatric disorder characterized by cognitive dysfunction. We report an association between DTNBP1 genotype and general cognitive ability (g) in two independent cohorts, including 213 patients with schizophrenia or schizo-affective disorder and 126 healthy volunteers. These data suggest that DTNBP1 genetic variation influences human intelligence.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据