期刊
MOLECULES
卷 11, 期 6, 页码 383-392出版社
MDPI
DOI: 10.3390/11060383
关键词
quinazolinone; phase transfer catalyst; synthesis; antifungal activity
A simple, efficient, and general method has been developed for the synthesis of various 3-alkylquinazolin-4-one derivatives from quinazolin-4-one treated with alkyl bromides under phase transfer catalysis condition. The structures of the compounds were characterized by elemental analysis, IR, H-1-NMR and C-13-NMR spectra. Title compound 6-bromo-3-propylquinazolin-4-one (3h) was found to possess good antifungal activity.
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