期刊
FERTILITY AND STERILITY
卷 85, 期 6, 页码 1784-1790出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2005.11.045
关键词
biochemistry; follicular phase; recurrent miscarriage
Objective: The study was designed to compare the follicular phase of women with recurrent pregnancy loss and a healthy contrl group. It is possible that a defective or aberrant follicular phase may be associated with poor oocyte quality leading to a production of an embryo with compromised quality and hence early pregnancy loss. Design: Prospective case-control study. Setting: A tertiary care hospital of Sheffield, UK. Patient(s): Thirty-four women with recurrent miscarriage and 10 women with no previous history of miscarriage and regular menstrual cycles (control group) were recruited. Intervention(s): The characteristics studied included Doppler assessment of blood flow to the follicle and the endometrium. Simultaneously, serum concentrations of biochemical markers such as anti-Mullerian hormone, inhibin B, FSH, LH, and P were compared in the two groups. Main Outcome Measure(s): Differences in the two groups. Result(s): We were unable to detect significant differences in various biochemical and ultrasound measurements in the follicular phase between women with recurrent miscarriage and a control group, was absent in women with recurrent miscarriage. Conclusion(s): There may be subtle derangements of the feedback mechanism responsible for regulation of follicle development in this group of women. However, there were no obvious differences in the follicular phase of women with recurrent miscarriage and a healthy control group.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据