期刊
NEURON
卷 50, 期 5, 页码 799-812出版社
CELL PRESS
DOI: 10.1016/j.neuron.2006.04.031
关键词
-
资金
- NINDS NIH HHS [R01 NS046424, R21 NS041255, NS46424, NS41255] Funding Source: Medline
When performing tasks, humans are thought to adopt task sets that configure moment-to-moment data processing. Recently developed mixed blocked/eventrelated designs allow task set-related signals to be extracted in fMRI experiments, including activity related to cues that signal the beginning of a task block, set-maintenance activity sustained for the duration of a task block, and event-related signals for different trial types. Data were conjointly analyzed from mixed design experiments using ten different tasks and 183 subjects. Dorsal anterior cingulate cortex/medial superior frontal cortex (dACC/msFC) and bilateral anterior insula/frontal operculum (al/fO) showed reliable start-cue and sustained activations across all or nearly all tasks. These regions also carried the most reliable error-related signals in a subset of tasks, suggesting that the regions form a core task-set system. Prefrontal regions commonly related to task control carried task-set signals in a smaller subset of tasks and lacked convergence across signal types.
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