期刊
JOURNAL OF ANTIBIOTICS
卷 59, 期 6, 页码 362-365出版社
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2006.52
关键词
Aspergillus sp.; diphenyl ether; asterric acid; anthraquinone; cytotoxicity
A new diphenyl ether dimethyl 2,3 ' dimethylosoate (1) together with three known compounds monomethylsulochrin (2), emodin (3), and questin (4) were isolated through bioassay-guided fractionations from the culture of a marine-derived fungus Aspergillus sp. B-F-2. The structures of these compounds were determined by spectroscopic methods. Cytotoxicities of compounds 1 and 2 against K562 cell line were preliminarily evaluated by the MTT method and flow cytometry.
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