期刊
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
卷 55, 期 2, 页码 89-94出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2005.10.013
关键词
Streptococcus pneumoniae; urinary antigen assay; children
The aim of the study was to evaluate the Binax Now rapid immunochromatographic test (ICT) for the detection of Streptococcus pneumoniae urinary antigen in children suffering from potentially pneumococcal infections. A total of 287 patients, with a median age of 34.9 months and divided into 3 groups, were Studied; the first group of patients with a suspected pneumococcal infection (n = 112), the second group with infections symptoms nonsuggestive of a pneumococcal infection (n = 54), and the third group was composed of asymptomatic children (n = 121). In group 1, sensitivity of ICT was 100% and specificity was 55.9% (95% confidence interval, 44.1- 67.7). Forty-six (85.1%) patients from the second group were true negatives. Twenty-five (20.7%) patients front the third study group were nasopharyngeal pneumococcal carriers, and the ICT was positive in 13 carriers (10.7%). The high sensitivity level of ICT in our study indicates that a negative test Could rule out a pneumococcal infection, contrasted with a poor specificity. (c) 2006 Elsevier Inc. All rights reserved.
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