期刊
MOVEMENT DISORDERS
卷 21, 期 6, 页码 772-776出版社
WILEY-LISS
DOI: 10.1002/mds.20802
关键词
idiopathic cerebellar ataxia; executive function; multiple system atrophy
Dementia represents an exclusion criterion for the diagnosis of multiple system atrophy (MSA), but there have been reports of fronto-executive dysfunction in patients with MSA of the striatonigral type (MSA-P). To study the cognitive profile of MSA, 20 patients with MSA of the cerebellar type (MSA-C) were subjected to an extensive neuropsychological test battery comprising tests for IQ, attention, verbal and visuo-spatial memory, as well as executive function. There was evidence for impaired verbal memory and verbal fluency. Test performance was not related to the severity of motor disability. Regarding the similar cognitive syndrome of MSA-P, the otherwise subclinical problems in MSA-C result from subcortical rather than from cerebellar dysfunction. (c) 2006 Movement Disorder Society.
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