期刊
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
卷 18, 期 3, 页码 356-363出版社
AMER PSYCHIATRIC PUBLISHING, INC
DOI: 10.1176/appi.neuropsych.18.3.356
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资金
- NIMH NIH HHS [R01 MH059708-06, MH59708 R01, R01 MH059708] Funding Source: Medline
Cognitive impairment, particularly in the domain of executive functioning, has been demonstrated to predict poorer antidepressant medication treatment response. In this investigation, neuropsychological functioning was evaluated as a predictor of depression treatment response among 59 patients with multiple sclerosis. Performance on a Stroop task accounted for 28.7% of the variance in poorer pharmacologic antidepressant treatment response, as compared to less than 1% of the variance in two psychotherapy conditions. These results provide preliminary evidence to suggest that performance on neuropsychological measures may predict antidepressant treatment response in multiple sclerosis.
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