期刊
PROCESS BIOCHEMISTRY
卷 41, 期 6, 页码 1303-1310出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.procbio.2006.01.001
关键词
solid-state fermentation; submerged fermentation; fungal kinetics; Paecilomyces fumosoroseus; insecticidal metabolites; carbon distribution
Dipicolinic acid (DPA) and oxalic acid (OXA) are insecticidal metabolites produced by the entomopathogenic fungus Paecilomyces fumosoroseus. A chemically defined medium was used to investigate the influence of the culture system on the carbon distribution in the fermentation products and the adaptative response to zinc limitation. In solid-state fermentation, carbon was mainly employed for biomass production, while in submerged fermentation, it was significantly directed to synthesis of DPA, OXA and other compounds, especially under zinc limitation. In solid-state fermentation, OXA and DPA were growth-associated products, while in submerged fermentation at low zinc levels, OXA and DPA were partially-growth-associated, perhaps because the metabolism was redirected when zinc became limiting. Entomopathogenic fungal action can be enhanced by the use of insecticidal metabolites, since our results show that biomass and metabolites production vary according to the culture system, this fact should be considered to choose the most appropriate spore production system. (c) 2006 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据