期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 16, 期 11, 页码 2842-2845出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2006.03.020
关键词
IRAK-4; kinase; inflammation; kinase inhibitor
High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-associated kinase-4. (c) 2006 Elsevier Ltd. All rights reserved.
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