期刊
PLANTA MEDICA
卷 72, 期 7, 页码 590-595出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2006-931565
关键词
Saussurea conica; Asteraceae; conicaols A and B; conicaoside; NO production suppressing activity
Three new lignan derivatives, conicaols A and B and conicaoside, together with seven known compounds were identified from Saussurea conica. Their structures were elucidated by spectral methods including 1D and 2D NMR techniques. Six 2,3-dibenzylbutyrolactone-type lignans were biologically evaluated, and two of them, arctigenin and matairesinol, showed potent activity to suppress NO production in vitro in LPS-activated macrophages of SD rat.
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