期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 16, 期 11, 页码 2925-2928出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2006.03.011
关键词
quinolone; microwave irradiation; potential biologically active; biomedical screening
A series of N-substituted 4-aryl-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-diones were synthesized through a rapid one-pot four-component reaction under microwave irradiation. The method has the advantages of excellent yields (82-96%) and short reaction time (4-9 min). We provide new series of potential biologically active compounds for biomedical screening. (c) 2006 Elsevier Ltd. All rights reserved.
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