期刊
FEBS LETTERS
卷 580, 期 14, 页码 3409-3416出版社
WILEY
DOI: 10.1016/j.febslet.2006.05.014
关键词
genome; dimorphic fungus; sexual cycle; mating; type genes; Penicillium marneffei
All meiotic genes (except HOP1) and genes encoding putative pheromone processing enzymes, pheromone receptors and pheromone response pathways proteins in Aspergillus fumigatus and Aspergillus nidulans and a putative MAT-1 alpha box mating-type gene were present in the Penicillium marneffei genome. A putative MAT-2 high-mobility group mating-type gene was amplified from a MA T-1 alpha box mating-type gene-negative P. marneffei strain. Among 37 P. marneffei patient strains, MAT-1 alpha a box and MAT-2 high-mobility group mating-type genes were present in 23 and 14 isolates, respectively. We speculate that A marneffei can potentially be a heterothallic fungus that does not switch mating type. (c) 2006 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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