期刊
NEUROLOGY
卷 66, 期 11, 页码 1756-1759出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.wnl.0000218162.80315.b9
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资金
- NIA NIH HHS [AG07232, AG08702] Funding Source: Medline
- NINDS NIH HHS [R01 NS42859] Funding Source: Medline
Pathologic findings, including cerebellar changes and brainstem Lewy bodies, distinguished 10 essential tremor (ET) cases from 12 controls. Numbers of torpedoes (p = 0.009) and Bergmann glia (p = 0.046) were increased in cases. Six cases (60%) had Lewy bodies vs 2 controls (16.7%) (odds ratio 7.5, 95% CI 1.04 to 54.1; p = 0.035). Four of these six had an atypical distribution of brainstem Lewy bodies. ET may be pathologically heterogeneous.
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