期刊
ANNALS OF NUTRITION AND METABOLISM
卷 60, 期 1, 页码 62-68出版社
KARGER
DOI: 10.1159/000335468
关键词
Probiotic yogurt; Oxidative stress; Pregnancy
资金
- Tehran University of Medical Sciences, Iran [1096]
Background: Due to the enhanced oxygen requirement of the mitochondria-rich placenta primarily during the third trimester, pregnancy is associated with elevated levels of oxidative stress. This study was designed to determine the effects of daily consumption of probiotic yogurt on oxidative stress among Iranian pregnant women. Methods: This randomized single-blind controlled clinical trial was performed among 70 pregnant women, singleton primigravida, aged 18-30 in their third trimester. Subjects were randomly assigned to two groups to consume 200 g/day of either conventional yogurt (n = 33) or probiotic yogurt (n = 37) for 9 weeks. Fasting blood samples were taken at baseline and after a 9-week intervention to measure oxidative stress parameters. Results: Consumption of probiotic yogurt resulted in increased erythrocyte glutathione reductase (GR) levels as compared to the conventional yogurt (p = 0.01). Despite the significant effect of probiotic yogurt consumption on plasma glutathione (67.9 mu mol/l, p = 0.01), erythrocyte glutathione peroxidase (163 mmol/min/ml, p = 0.04) and serum 8-oxo-7,8-dihydroguanine levels (-74.3 ng/ml, p = 0.04), no significant differences were found between the two yogurts in terms of their effects on the mentioned parameters. Conclusion: Consumption of probiotic yogurt among pregnant women resulted in increased levels of erythrocyte GR as compared to the conventional yogurt, but could not affect other indices of oxidative stress. Copyright (C) 2012 S. Karger AG, Basel
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据