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1,3-Diketones from acid chlorides and ketones: A rapid and general one-pot synthesis of pyrazoles

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卷 8, 期 13, 页码 2675-2678

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AMER CHEMICAL SOC
DOI: 10.1021/ol060570p

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1,3-Diketones were synthesized directly from ketones and acid chlorides and were then converted in situ into pyrazoles by the addition of hydrazine. This method is extremely fast, general, and chemoselective, allowing for the synthesis of previously inaccessible pyrazoles and synthetically demanding pyrazole-containing fused rings.

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