4.4 Review

The postoperative surveillance of patients with colon cancer and rectal cancer

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AMERICAN JOURNAL OF SURGERY
卷 192, 期 1, 页码 100-108

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EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjsurg.2006.01.053

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colorectal; cancer; postoperative surveillance; follow-up programs; PET scan; CEA assays

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Background: Colon cancer is relatively common; however, the results of treatment have marginally improved over the last half century. though about 85% of patients have colorectal tumors resected with curative intent, a significant number of these patients will eventually die from cancer. As a result, many clinicians have advocated intensive follow-up in such patients as an attempt to increase survival. Data Sources: A review of the literature focusing on studies that have specifically addressed postoperative surveillance programs in patients with colorectal cancer was conducted. Only studies with level A evidence were included. Further references were obtained through cross-referencing the bibliography cited in each work. Conclusion: One of the six prospective randomized studies demonstrated a statistically significant survival benefit. Undoubtedly, survival benefits can be shown with a well-designed evidence-based follow-up strategy. However, well-designed large prospective multi-institutional randomized studies are needed to establish a consensus for follow-up. (c) 2006 Excerpta Medica Inc. All rights reserved.

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