期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 6, 期 7, 页码 765-770出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138955706777698642
关键词
myostatin; muscle; adipose tissue; rhabdomyosarcoma; myostatin antagonism; myostatin processing and signaling; therapeutic approaches
Myostatin is a negative regulator of muscle mass. Important advances in our understanding of the complex biology of this factor have revealed the therapeutic potential of antagonizing the myostatin pathway. Here we present the rationale for evaluating anti-myostatin therapies in human muscle-wasting disorders.
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