期刊
JOURNAL OF BACTERIOLOGY
卷 188, 期 14, 页码 5289-5292出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00526-06
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- Intramural NIH HHS Funding Source: Medline
The chlamydial histone-like proteins, Hc1 and Hc2, function as global regulators of chromatin structure and gene expression. Hc1 and Hc2 expression and activity are developmentally regulated. A small metabolite that disrupts Hc1 interaction with DNA also disrupts Hc2 interactions; however, the small regulatory RNA that inhibits Hc1 translation is specific to Hc1.
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