4.5 Article

Consumption of antioxidant-rich beverages and risk for breast cancer in French women

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ANNALS OF EPIDEMIOLOGY
卷 16, 期 7, 页码 503-508

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.annepidem.2005.09.011

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cohort studies; tea; herbal tea; wine; coffee; fruit juices; antioxidants; breast cancer

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PURPOSE: The objective of the study is to evaluate the relation between antioxidant-rich beverages and the incidence of breast cancer. METHODS: This prospective study consisted of 4396 women without a history of cancer who were participants in the French Supplementation en Vitamines et Mineraux Antioxydants Study. Beverage consumption was estimated by using three nonconsecutive 24-hour recalls. Incident cancer cases were identified through clinical examinations performed every other year, including, e.g., a screening mammogram, and through a monthly health questionnaire. RESULTS: During the median 6.6 years of follow-up, 95 breast cancers were diagnosed. In a multivariate model, an inverse association between herbal tea consumption and risk for breast cancer was observed (compared with nondrinkers, drinking 1 to 149 mL/d; relative risk [RR], 0.93; 95% confidence interval [CI], 0-48-1.80, and for >= 150 mL/d; RR, 0.43; 95% CI 0.204.94; P for trend = 0.04). Consumption of coffee, tea, fruit juices, or wine was not associated with risk for breast cancer. CONCLUSION: Results of this study suggest that consumption of herbal tea may have a role in the prevention of breast cancer.

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