期刊
NEUROIMAGE
卷 31, 期 3, 页码 1306-1314出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2006.01.027
关键词
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We used blood oxygen-dependent (BOLD) fMRI technique at 1.5 T to examine brain regions associated with language comprehension in normally developing children, age 5 to 10 years. Twenty-three children participated in the study using an auditory semantic decision task which varied in task difficulty. Analysis of individual participants' data showed patterns of activation largely consistent with previous neuro-imaging findings in adult language processing. Group data analysis also showed a strong left-lateralized pattern of activation that closely resembles those typically observed in adults. In addition, significant activation in the left fusiform gyrus was observed and was associated with task accuracy. This finding suggests that auditory semantic processing in young children may recruit cortical regions associated with word reading in adults prior to the initiation of a semantic category decision, a process which is consistent with patterns of early word recognition process and language development. (c) 2006 Elsevier Inc. All rights reserved.
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