期刊
ANNALS OF NEUROLOGY
卷 64, 期 4, 页码 455-460出版社
WILEY
DOI: 10.1002/ana.21434
关键词
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资金
- Ministero dell 'Universit a e della Ricerca, MUR
Humans have an individual profile of the electroencephalographic power spectra at the 8 to 16Hz frequency during non-rapid eye movement sleep that is stable over time and resistant to experimental perturbations. We tested the hypothesis that this electroencephalographic fingerprint is genetically determined, by recording 40 monozygotic and dizygotic twins during baseline and recovery sleep after prolonged wakefulness. We show a largely greater similarity within monozygotic than dizygotic pairs, resulting in a heritability estimate of 96%, not influenced by sleep need and intensity. If replicated, these results will establish the electroencephalographic profile during sleep as one of the most heritable traits of humans.
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