期刊
JOURNAL OF BACTERIOLOGY
卷 188, 期 13, 页码 4996-5001出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00317-06
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- NIAID NIH HHS [R01 AI048935, R01 AI067737, 1R01AI067737-01, 1R01AI48935] Funding Source: Medline
The bactericidal activity of Streptococcus pneumoniae toward Staphylococcus aureus is mediated by hydrogen peroxide. Catalase eliminated this activity. Pneumococci grown anaerobically or genetically lacking pyruvate oxidase (SpxB) were not bactericidal, nor were nonpneumococcal streptococci. These results provide a possible mechanistic explanation for the interspecies interference observed in epidemiologic studies.
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