期刊
CELLULAR AND MOLECULAR LIFE SCIENCES
卷 63, 期 13, 页码 1494-1500出版社
SPRINGER BASEL AG
DOI: 10.1007/s00018-006-6112-9
关键词
synapses; serotonin; ATP; paracrine; sensory afferent fibers
资金
- NIDCD NIH HHS [R01 DC007630, R01 DC000374] Funding Source: Medline
Taste bud cells communicate with sensory afferent fibers and may also exchange information with adjacent cells. Indeed, communication between taste cells via conventional and/or novel synaptic interactions may occur prior to signal output to primary afferent fibers. This review discusses synaptic processing in taste buds and summarizes results showing that it is now possible to measure real-time release of synaptic transmitters during taste stimulation using cellular biosensors. There is strong evidence that scrotonin and ATP play a role in cell-to-cell signaling and sensory output in the gustatory end organs.
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