期刊
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL
卷 39, 期 4, 页码 385-387出版社
SOC BRASILEIRA MEDICINA TROPICAL
DOI: 10.1590/S0037-86822006000400014
关键词
Chagas' disease; diagnosis; serology; chemiluminescence; PCR
While testing 414 sera for the diagnosis of Chagas' disease, the conventional reactions of indirect hemagglutination, indirect immunofluorescence and the immunosorbent assay showed a sensitivity of 95.7%, 100% and 98.2% and a specificity of 98%, 98% and 96.4%, respectively, and an excellent association using Fisher's exact test. Chemiluminescence presented 100% sensitivity and 89.6% specificity, while PCR showed 100% specificity and 1.2% sensitivity It is believed that the three conventional serological reactions are still adequate for diagnosing Chagas' disease.
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