期刊
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
卷 42, 期 3, 页码 342-346出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/01.qai.0000219785.81163.67
关键词
HIV; injecting drug user; prison; MSM; Iran
Objectives: To determine the prevalence and correlates of HIV-1 infection among community-based injecting drug users (IDUs) in Tehran, Iran. Methods: In October 2004, 213 IDUs were recruited from a drop-in center and its neighboring parks and streets in Tehran. Participants were interviewed using a structured questionnaire regarding their sociodemographics and HIV risk characteristics, and specimens of oral mucosal transudate were collected and tested for HIV-I antibodies. Data were analyzed using X 2 and multiple logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CI). Results: The prevalence of HIV-I infection was 23.2% (48 of 207) among male injecting drug users. In the multivariable analysis, a history of shared drug injection inside prison (OR, 2.45; 95% Cl, 1.01-5.97) and that of multiple incarcerations (OR, 3.13; 95% Cl, 1.08-9.09) were associated with significantly higher prevalence of HIV-1 infection. Conclusions: The prevalence of HIV-1 infection has reached an alarming level among IDUs in Tehran, with incarceration-related exposures revealed to be the main correlates of HIV-1 infection. Urgent and comprehensive harm reduction programs for drug users in prison and those in the community in Tehran are of prime importance to prevent further transmission of HIV infection.
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