期刊
GENETICS
卷 173, 期 3, 页码 1813-1816出版社
GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.106.057927
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资金
- NHGRI NIH HHS [F32 HG002649, F32 HG02649-01] Funding Source: Medline
- NIGMS NIH HHS [P50 GM071508, R01 GM046406] Funding Source: Medline
We demonstrate a new method, microarray-assisted bulk segregant analysis, for mapping traits in yeast by genotyping pooled segregants. We apply a probabilistic model to the progeny of a single cross and as little as two microarray hybridizations to reliably map an auxotrophic marker, a Mendelian trait, and a major-effect quantitative trait locus.
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