期刊
NANO LETTERS
卷 6, 期 7, 页码 1505-1507出版社
AMER CHEMICAL SOC
DOI: 10.1021/nl0609955
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- NIGMS NIH HHS [GM-29554, R37 GM029554, R37 GM029554-25, R01 GM029554, R37 GM029554-24] Funding Source: Medline
- PHS HHS [N00014-98-1-0093] Funding Source: Medline
DNAzymes are catalytically active DNA molecules, which have previously been described in solution. Here, we organize these molecules into a series of two-dimensional (2D) arrays using a periodic arrangement of DNA structures based on the DNA double crossover motif. We demonstrate by means of atomic force microscopy that the DNAzymes are organized according to the design and that they retain their activity when attached in linear strings within the context of the 2D array.
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