期刊
CARDIOVASCULAR RESEARCH
卷 71, 期 2, 页码 259-268出版社
OXFORD UNIV PRESS
DOI: 10.1016/j.cardiores.2006.03.002
关键词
atherosclerosis; oxygen radicals
There is increasing evidence that human atherosclerosis is associated with damage to the DNA of both circulating cells, and cells of the vessel wall. Reactive oxygen species are the most likely agents inducing DNA damage in atherosclerosis. DNA damage produces a variety of responses, including cell senescence, apoptosis and DNA repair. This review summarises the evidence for DNA damage in atherosclerosis, the cellular responses to damage and the mechanisms of signalling DNA damage. (c) 2006 European Society of Cardiology. Published by Elsevier B.V All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据