期刊
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
卷 78B, 期 2, 页码 291-295出版社
WILEY
DOI: 10.1002/jbm.b.30486
关键词
calcium phosphate; slurry; obturation; dentin permeability; hydraulic conductance; dentin hypersensitivity
资金
- NIDCR NIH HHS [DE05354] Funding Source: Medline
Treatments that obdurate dentin tubules have been used for reducing dentin hypersensitivity. The purpose of this study was to determine the effect of a treatment with a slurry of micron sized calcium phosphate on the hydraulic conductance (L-p) of etched dentin discs in vitro. The treatment slurry was prepared by mixing a powder mixture of dicalcium phosphate anhydrous and calcium hydroxide with a solution that contained sodium fluoride and carboxymethyl cellulose. The mean baseline L-p (in mL cm(-2) s(-1) H2O cm(-1)) was 2.07 +/- 1.45 (mean +/- SD; n = 13)). After one treatment and 2, 4, and 7 days of incubation in a protein-free saliva-like solution (SLS), the mean relative L-p, presented as % of baseline, were 65 +/- 16, 42 +/- 27, 36 +/- 26, and 33 +/- 27 (n = 13), respectively. The L-p values of the baseline and treatment after incubation in the SLS were significantly (P <= 0.05) different. Scanning electron microscopic examination showed partial obturation of dentin tubules in the treated dentin. X-ray diffraction and chemical analyses indicated the major product formed from the slurry was a fluoride-containing hydroxyapatite. Treatment appeared effective in further reducing L-p of dentin discs after incubation in the SLS. (c) 2006 Wiley Periodicals, Inc.
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