期刊
JOURNAL OF BONE AND MINERAL RESEARCH
卷 21, 期 8, 页码 1215-1223出版社
WILEY
DOI: 10.1359/JBMR.060508
关键词
anastrozole; tamoxifen; fracture; BMD; bone remodeling
Aromatase inhibitors reduce estrogen levels in postmenopausal women with breast cancer. Residual estrogen is an important determinant of bone turnover. Adjuvant anastrozole was associated with significant BMD loss and increased bone remodeling, whereas tamoxifen reduced bone marker levels.
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