期刊
NATURE NEUROSCIENCE
卷 9, 期 8, 页码 1001-1003出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn1725
关键词
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资金
- NEI NIH HHS [R01 EY014882, R01 EY014882-02, R01-EY012124, R01 EY014882-03, R01 EY012124, R01 EY014882-01A1, R01-EY014882] Funding Source: Medline
Lack of a sensory input not only alters the cortical circuitry subserving the deprived sense, but also produces compensatory changes in the functionality of other sensory modalities. Here we report that visual deprivation produces opposite changes in synaptic function in primary visual and somatosensory cortices in rats, which are rapidly reversed by visual experience. This type of bidirectional cross-modal plasticity is associated with changes in synaptic AMPA receptor subunit composition.
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