期刊
CURRENT HYPERTENSION REPORTS
卷 8, 期 4, 页码 298-303出版社
CURRENT SCIENCE INC
DOI: 10.1007/s11906-006-0068-x
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The kidneys play a central role in the long-term regulation of blood pressure and in the pathogenesis of hypertension. A common defect that has been found in all forms of hypertension examined to date is a hypertensive shift in the pressure-natriuresis relationship. A major objective of this brief review is to highlight some of the recent advances in our understanding of the mechanisms whereby the renal endothelia system, via endothelia type A- and endothelia type B-receptor activation, modulates renal pressure-natriuresis and blood pressure regulation under normal physiologic conditions and in certain forms of hypertension.
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