期刊
JOURNAL OF BONE AND MINERAL RESEARCH
卷 21, 期 8, 页码 1248-1255出版社
AMER SOC BONE & MINERAL RES
DOI: 10.1359/JBMR.060514
关键词
bone mechanics; bone quality; cancellous bone; bone remodeling; osteoporosis treatments
资金
- NIAMS NIH HHS [AR49570, R01 AR043784, R01 AR049828, R21 AR049570, AR049828, AR43784] Funding Source: Medline
We evaluated the effects of resorption cavities on cancellous bone strength using computational methods. Adding cavities to cancellous bone caused reductions in strength and stiffness that were greater than expected from the associated changes in bone volume and more pronounced when cavities were targeted to regions of high tissue strain.
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