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Cognitive control impairments in traumatic brain injury

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TAYLOR & FRANCIS INC
DOI: 10.1080/13803390600646860

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  1. NIMH NIH HHS [K01 MH01857, R21 MH073076] Funding Source: Medline

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The componential nature of impaired cognitive control following traumatic brain injury (TBI) remains uncertain. We examined regulative and evaluative components of cognitive control in mild and moderate-to-severe (M/S) TBI patients and demographically-matched comparison participants using the AX-CPT task. We also examined relationships of cognitive control impairment to ratings of cognitive, behavioral, and affective symptomatology on the Dysexecutive Questionnaire (DEX). Results revealed that M/S, but not mild TBI patients showed deficits in context-processing and post-error strategic adjustments-extent of impairments correlated with TBI-related symptomatology. Thus, patients with MISS TBI evidence cognitive control dysfunction in the processing and active maintenance of context representations.

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