4.4 Article

Peptide-capped gold nanoparticles: Towards artificial proteins

期刊

CHEMBIOCHEM
卷 7, 期 8, 页码 1141-1145

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbic.200600129

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biomimetics; complexity; nanotechnology; peptides; self-assembly

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Peptides can be designed to form self-assembled monoloyers on gold nanoporticles to give nonomaterials with some chemical properties analogous to those of proteins. A variety of molecular-recognition properties are readily integrated within the peptide monolayer. Monofunctionalized nanoporticles are obtained by using separation methods that have been optimized for proteins. Recent applications as artificial enzymes and artificial enzyme substrates are presented. The limitations and long-term potential of peptide-capped nanoparticles as artificial proteins ore discussed.

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