期刊
RESEARCH IN VETERINARY SCIENCE
卷 81, 期 1, 页码 158-164出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.rvsc.2005.09.001
关键词
morbillivirus; peste des petits ruminants virus; vaccine virus; phosphoprotein gene; nucleotide sequence; amino acid sequence
The nucleotide sequences of the phosphoprotein (P) gene of peste des petits ruminants (PPRV) vaccine virus (PPRV Sungri/96) belongs to Asian lineage have been determined and the deduced amino acid sequences were compared with another vaccine strain PPRV/Nigeria75/1 and with those of the other morbilliviruses. The 1652 nucleotides of the P gene encode a phosphoprotein of 509 amino acid residues (from nucleotide numbers 60 to 1587), which is 91% identical to that of PPRV/Nigeria75/1. The C protein consists of 177 amino acid residues and is 91% identical with that of PPRV/Nigeria75/1. The conserved mRNA editing site (5'TTAAA-AGGGCACAG) was present at positions 742-756 in the P gene, which is conserved in all other morbilliviruses. The CTT trinucleotide sequence is present at the N/P and P/M intergenic region, which is totally conserved in morbilliviruses. This will be the third sequence for the P gene of PPRV since that of the vaccine strain and a wild-type Turkish isolate has been published already. (c) 2005 Elsevier Ltd. All rights reserved.
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