期刊
JOURNAL OF BACTERIOLOGY
卷 188, 期 15, 页码 5635-5639出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00422-06
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The largest family of solute transporters (major facilitator superfamily [MFS]) includes proton-motive-force-driven secondary transporters. Several characterized MFS transporters utilize essential acidic residues that play a critical role in the energy-coupling mechanism during transport. Surprisingly, we show here that no single acidic residue plays an irreplaceable role in the Escherichia coli secondary multidrug transporter MdfA.
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