期刊
ANNALS OF FAMILY MEDICINE
卷 12, 期 2, 页码 134-141出版社
ANNALS FAMILY MEDICINE
DOI: 10.1370/afm.1618
关键词
lactose intolerance; dairy products; soy milk; adult
资金
- Weston A. Price Foundation
- Stanford University Program in Human Biology
PURPOSE This pilot study aimed to determine whether raw milk reduces lactose malabsorption and/or lactose intolerance symptoms relative to pasteurized milk. METHODS We performed a crossover trial involving 16 adults with self-reported lactose intolerance and lactose malabsorption confirmed by hydrogen (H-2) breath testing. Participants underwent 3, 8-day milk phases (raw vs 2 controls: pasteurized, soy) in randomized order separated by 1-week washout periods. On days 1 and 8 of each phase, milk consumption was 473 mL (16 oz); on days 2 to 7, milk dosage increased daily by 118 mL (4 oz), beginning with 118 mL (4 oz) on day 2 and reaching 710 mL (24 oz) on day 7. Outcomes were area under the breath H-2 curve (AUC Delta H-2) and self-reported symptom severity (visual analog scales: flatulence/gas, audible bowel sounds, abdominal cramping, diarrhea). RESULTS AUC Delta H-2 (mean +/- standard error of the mean) was higher for raw vs pasteurized on day 1 (113 +/- 21 vs 71 +/- 12 ppm . min . 10(-2), respectively, P =.01) but not day 8 (72 +/- 14 vs 74 +/- 15 ppm . min . 10(-2), respectively, P = .9). Symptom severities were not different for raw vs pasteurized on day 7 with the highest dosage (P > . 7). AUC Delta H-2 and symptom severities were higher for both dairy milks compared with soy milk. CONCLUSIONS Raw milk failed to reduce lactose malabsorption or lactose intolerance symptoms compared with pasteurized milk among adults positive for lactose malabsorption. These results do not support widespread anecdotal claims that raw milk reduces the symptoms of lactose intolerance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据