期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 71, 期 16, 页码 6135-6140出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo060863w
关键词
-
资金
- NIGMS NIH HHS [GM 35249] Funding Source: Medline
The stereoselective synthesis of unsaturated organotrifluoroborates by using the Wittig and Horner-Wadsworth-Emmons olefination is described. These reactions were general for both alkyl- and aryltrifluoroborates. The synthesis of di- and trisubstituted olefins was achieved by using formyl- and acetyl-substituted organotrifluoroborates. The products were isolated in moderate to excellent yield. The Wittig reaction with nonstabilized ylides was performed under salt free conditions in most cases to obtain the Z-isomer. The E-isomer was accessed by using preformed stabilized ylides. The Horner-Wadsworth-Emmons reaction also gave the E-isomer as expected.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据