期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 12, 期 23, 页码 5972-5990出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.200600236
关键词
C-C coupling; heterogeneous catalysis; immobilization; microreactors; organic chemistry
The concepts article describes enabling techniques (solid-phase assisted synthesis, new reactor design, microwave irradiation and new solvents) in organic chemistry and emphasizes the combination of several of them for creating new synthetic technology platforms. Particular focus is put on the combination of immobilized catalysts as well as biocatalysts with continuous flow processes. In this context, the PASSflow continuous flow technique fulfils both chemical as well as chemical engineering requirements. It combines reactor design with optimized, monolithic solid phases as well as reversible immobilization techniques for performing small as well as large scale synthesis with heterogenized catalysts under continuous flow conditions.
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