期刊
STATISTICS IN MEDICINE
卷 25, 期 16, 页码 2846-2866出版社
WILEY
DOI: 10.1002/sim.2257
关键词
screening; mixture models; prostate cancer
类别
资金
- NCI NIH HHS [U01 CA097414-05, U01 CA097414-06, U01 CA97414, U01 CA097414] Funding Source: Medline
Introduction of screening for prostate cancer using the prostate-specific antigen (PSA) marker of the disease led to remarkable dynamics of the incidence of the disease observed in the last two decades. A statistical model is used to provide a link between dissemination of PSA and the observed transient population responses. The model is used to estimate lead time, overdiagnosis and other relevant characteristics of prostate cancer screening. Copyright (c) 2006 John Wiley & Sons, Ltd.
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